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A pot-economical and diastereoselective synthesis involving catalyst-free click reaction for fused-triazolobenzodiazepines

  • Xiaofeng Zhang
  • , Sanjun Zhi
  • , Wei Wang
  • , Shuai Liu
  • , Jerry P. Jasinski
  • , Wei Zhang
  • University of Massachusetts Boston
  • Huaiyin Normal University
  • Shaanxi Normal University
  • Keene State College

Research output: Contribution to journalArticlepeer-review

Abstract

A pot-economical synthesis involving sequential [3 + 2] cycloadditions of an azomethine ylide and an azide-alkyne (click reaction) has been developed for diastereoselective synthesis of novel triazolobenzodiazepine-containing polycyclic compounds. A new example of catalyst-free click chemistry of non-strained alkynes is also disclosed.

Original languageEnglish
Pages (from-to)2642-2646
Number of pages5
JournalGreen Chemistry
Volume18
Issue number9
DOIs
StatePublished - 2016

ASJC Scopus Subject Areas

  • Environmental Chemistry
  • Pollution

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