A Seed Mismatch Enhances Argonaute2-Catalyzed Cleavage and Partially Rescues Severely Impaired Cleavage Found in Fish

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)1095-1107.e5
JournalMolecular Cell
Volume68
Issue number6
DOIs
StatePublished - 2017
Externally publishedYes

ASJC Scopus Subject Areas

  • Molecular Biology
  • Cell Biology

Keywords

  • AGO2
  • Argonaute
  • in vitro slicing
  • kinetic analysis
  • miR-451 processing
  • miRNA
  • RISC
  • RNAi
  • siRNA design

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