Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

Michael V. Holmes; Caroline E. Dale; Luisa Zuccolo; Richard J. Silverwood; Yiran Guo; Zheng Ye; David Prieto-Merino; Abbas Dehghan; Stella Trompet; Andrew Wong; Alana Cavadino; Dagmar Drogan; Sandosh Padmanabhan; Shanshan Li; Ajay Yesupriya; Maarten Leusink; Johan Sundstrom; Jaroslav A. Hubacek; Hynek Pikhart; Daniel I. Swerdlow; Andrie G. Panayiotou; Svetlana A. Borinskaya; Chris Finan; Sonia Shah; Karoline B. Kuchenbaecker; Tina Shah; Jorgen Engmann; Lasse Folkersen; Per Eriksson; Fulvio Ricceri; Olle Melander; Carlotta Sacerdote; Dale M. Gamble; Sruti Rayaprolu; Owen A. Ross; Stela McLachlan; Olga Vikhireva; Ivonne Sluijs; Robert A. Scott; Vera Adamkova; Leon Flicker; Frank M. Van Bockxmeer; Christine Power; Pedro Marques-Vidal; Tom Meade; Michael G. Marmot; Jose M. Ferro; Sofia Paulos-Pinheiro; Steve E. Humphries; Philippa J. Talmud; Irene Mateo Leach; Niek Verweij; Allan Linneberg; Tea Skaaby; Pieter A. Doevendans; Maarten J. Cramer; Pim Van Der Harst; Olaf H. Klungel; Nicole F. Dowling; Anna F. Dominiczak; Meena Kumari; Andrew N. Nicolaides; Cornelia Weikert; Heiner Boeing; Shah Ebrahim; Tom R. Gaunt; Jackie F. Price; Lars Lannfelt; Anne Peasey; Ruzena Kubinova; Andrzej Pajak; Sofia Malyutina; Mikhail I. Voevoda; Abdonas Tamosiunas; Anke H. Maitland-van Der Zee; Paul E. Norman; Graeme J. Hankey; Manuela M. Bergmann; Albert Hofman; Oscar H. Franco; Jackie Cooper; Jutta Palmen; Wilko Spiering; Pim A. De Jong; Diana Kuh; Rebecca Hardy; Andre G. Uitterlinden; M. Arfan Ikram; Ian Ford; Elina Hyppönen; Osvaldo P. Almeida; Nicholas J. Wareham; Kay Tee Khaw; Anders Hamsten; Lise Lotte N. Husemoen; Anne Tjønneland; Janne S. Tolstrup; Eric Rimm; Joline W.J. Beulens; W. M.Monique Verschuren; N. Charlotte Onland-Moret; Marten H. Hofker; S. Goya Wannamethee; Peter H. Whincup; Richard Morris; Astrid M. Vicente; Hugh Watkins; Martin Farrall; J. Wouter Jukema; James Meschia; L. Adrienne Cupples; Stephen J. Sharp; Myriam Fornage; Charles Kooperberg; Andrea Z. LaCroix; James Y. Dai; Matthew B. Lanktree; David S. Siscovick; Eric Jorgenson; Bonnie Spring; Josef Coresh; Yun R. Li; Sarah G. Buxbaum; Pamela J. Schreiner; R. Curtis Ellison; Michael Y. Tsai; Sanjay R. Patel; Susan Redline; Andrew D. Johnson; Ron C. Hoogeveen; Hakon Hakonarson; Jerome I. Rotter; Eric Boerwinkle; Paul I.W. De Bakker; Mika Kivimaki; Folkert W. Asselbergs; Naveed Sattar; Debbie A. Lawlor; John Whittaker; George Davey Smith; Kenneth Mukamal; Bruce M. Psaty; James G. Wilson; Leslie A. Lange; Ajna Hamidovic; Børge G. Nordestgaard; Martin Bobak; David A. Leon; Claudia Langenberg; Tom M. Palmer; Alex P. Reiner; Brendan J. Keating; Frank Dudbridge; Juan P. Casas

doi:10.1136/bmj.g4164

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

Michael V. Holmes
, Caroline E. Dale
, Luisa Zuccolo
, Richard J. Silverwood
, Yiran Guo
, Zheng Ye
, David Prieto-Merino
, Abbas Dehghan
, Stella Trompet
, Andrew Wong
, Alana Cavadino
, Dagmar Drogan
, Sandosh Padmanabhan
, Shanshan Li
, Ajay Yesupriya
, Maarten Leusink
, Johan Sundstrom
, Jaroslav A. Hubacek
, Hynek Pikhart
, Daniel I. Swerdlow

Andrie G. Panayiotou, Svetlana A. Borinskaya, Chris Finan, Sonia Shah, Karoline B. Kuchenbaecker, Tina Shah, Jorgen Engmann, Lasse Folkersen, Per Eriksson, Fulvio Ricceri, Olle Melander, Carlotta Sacerdote, Dale M. Gamble, Sruti Rayaprolu, Owen A. Ross, Stela McLachlan, Olga Vikhireva, Ivonne Sluijs, Robert A. Scott, Vera Adamkova, Leon Flicker, Frank M. Van Bockxmeer, Christine Power, Pedro Marques-Vidal, Tom Meade, Michael G. Marmot, Jose M. Ferro, Sofia Paulos-Pinheiro, Steve E. Humphries, Philippa J. Talmud, Irene Mateo Leach, Niek Verweij, Allan Linneberg, Tea Skaaby, Pieter A. Doevendans, Maarten J. Cramer, Pim Van Der Harst, Olaf H. Klungel, Nicole F. Dowling, Anna F. Dominiczak, Meena Kumari, Andrew N. Nicolaides, Cornelia Weikert, Heiner Boeing, Shah Ebrahim, Tom R. Gaunt, Jackie F. Price, Lars Lannfelt, Anne Peasey, Ruzena Kubinova, Andrzej Pajak, Sofia Malyutina, Mikhail I. Voevoda, Abdonas Tamosiunas, Anke H. Maitland-van Der Zee, Paul E. Norman, Graeme J. Hankey, Manuela M. Bergmann, Albert Hofman, Oscar H. Franco, Jackie Cooper, Jutta Palmen, Wilko Spiering, Pim A. De Jong, Diana Kuh, Rebecca Hardy, Andre G. Uitterlinden, M. Arfan Ikram, Ian Ford, Elina Hyppönen, Osvaldo P. Almeida, Nicholas J. Wareham, Kay Tee Khaw, Anders Hamsten, Lise Lotte N. Husemoen, Anne Tjønneland, Janne S. Tolstrup, Eric Rimm, Joline W.J. Beulens, W. M.Monique Verschuren, N. Charlotte Onland-Moret, Marten H. Hofker, S. Goya Wannamethee, Peter H. Whincup, Richard Morris, Astrid M. Vicente, Hugh Watkins, Martin Farrall, J. Wouter Jukema, James Meschia, L. Adrienne Cupples, Stephen J. Sharp, Myriam Fornage, Charles Kooperberg, Andrea Z. LaCroix, James Y. Dai, Matthew B. Lanktree, David S. Siscovick, Eric Jorgenson, Bonnie Spring, Josef Coresh, Yun R. Li, Sarah G. Buxbaum, Pamela J. Schreiner, R. Curtis Ellison, Michael Y. Tsai, Sanjay R. Patel, Susan Redline, Andrew D. Johnson, Ron C. Hoogeveen, Hakon Hakonarson, Jerome I. Rotter, Eric Boerwinkle, Paul I.W. De Bakker, Mika Kivimaki, Folkert W. Asselbergs, Naveed Sattar, Debbie A. Lawlor, John Whittaker, George Davey Smith, Kenneth Mukamal, Bruce M. Psaty, James G. Wilson, Leslie A. Lange, Ajna Hamidovic, Børge G. Nordestgaard, Martin Bobak, David A. Leon, Claudia Langenberg, Tom M. Palmer, Alex P. Reiner, Brendan J. Keating, Frank Dudbridge, Juan P. Casas

University College London
University of Pennsylvania
London School of Hygiene and Tropical Medicine
University of Bristol
Children’s Hospital of Philadelphia
BGI-Shenzhen
University of Cambridge
Erasmus University Rotterdam
Leiden University
German Institute of Human Nutrition Potsdam-Rehbruecke
University of Glasgow
Harvard University
Centers for Disease Control and Prevention
Utrecht University
Uppsala University
Institute for Clinical and Experimental Medicine
Cyprus University of Technology
Russian Academy of Sciences
Karolinska Institutet
Azienda Sanitaria Ospedaliera Molinette San Giovanni Battista Di Torino
Lund University
Mayo Clinic Jacksonville, FL
University of Edinburgh
University of Western Australia
University of Lausanne
University of Lisbon
Instituto Nacional de Saúde Doutor Ricardo Jorge
University of Groningen
University of Copenhagen
Royal Netherlands Academy of Arts and Sciences
Vascular Screening and Diagnostic Centre, Nicosia
Imperial College London
Cyprus Cardiovascular Disease Educational and Research Trust
Czech National Institute of Public Health
Jagiellonian University Medical College
Russian Academy of Medical Sciences - Siberian Branch
Novosibirsk State Medical University
Novosibirsk State University
Lithuanian University of Health Sciences
Sir Charles Gairdner Hospital
University of South Australia
South Australian Health And Medical Research Institute
Royal Perth Hospital
Danish Cancer Society
University of Southern Denmark
National Institute of Public Health and the Environment
St. George's University of London
Instituto Gulbenkian Ciencia
University of Oxford
Boston University
Framingham Heart Study
University of Texas Health Science Center at Houston
Fred Hutchinson Cancer Research Center
McMaster University
New York Academy of Medicine
Kaiser Permanente
Northwestern University
Johns Hopkins University
Jackson State University
University of Minnesota Twin Cities
Brigham and Women’s Hospital
Beth Israel Deaconess Medical Center
Baylor College of Medicine
Los Angeles Biomedical Research Institute
British Heart Foundation, Glasgow Cardiovascular Research Centre, University of Glasgow
GlaxoSmithKline
University of Washington
Group Health Cooperative
University of Mississippi
University of North Carolina at Chapel Hill
University of New Mexico
University of Warwick

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	g4164
Journal	BMJ
Volume	349
DOIs	https://doi.org/10.1136/bmj.g4164
State	Published - Jul 10 2014
Externally published	Yes

ASJC Scopus Subject Areas

General Medicine

Access to Document

10.1136/bmj.g4164

Cite this

Holmes, M. V., Dale, C. E., Zuccolo, L., Silverwood, R. J., Guo, Y., Ye, Z., Prieto-Merino, D., Dehghan, A., Trompet, S., Wong, A., Cavadino, A., Drogan, D., Padmanabhan, S., Li, S., Yesupriya, A., Leusink, M., Sundstrom, J., Hubacek, J. A., Pikhart, H., ... Casas, J. P. (2014). Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ, 349, Article g4164. https://doi.org/10.1136/bmj.g4164

Holmes, MV, Dale, CE, Zuccolo, L, Silverwood, RJ, Guo, Y, Ye, Z, Prieto-Merino, D, Dehghan, A, Trompet, S, Wong, A, Cavadino, A, Drogan, D, Padmanabhan, S, Li, S, Yesupriya, A, Leusink, M, Sundstrom, J, Hubacek, JA, Pikhart, H, Swerdlow, DI, Panayiotou, AG, Borinskaya, SA, Finan, C, Shah, S, Kuchenbaecker, KB, Shah, T, Engmann, J, Folkersen, L, Eriksson, P, Ricceri, F, Melander, O, Sacerdote, C, Gamble, DM, Rayaprolu, S, Ross, OA, McLachlan, S, Vikhireva, O, Sluijs, I, Scott, RA, Adamkova, V, Flicker, L, Van Bockxmeer, FM, Power, C, Marques-Vidal, P, Meade, T, Marmot, MG, Ferro, JM, Paulos-Pinheiro, S, Humphries, SE, Talmud, PJ, Leach, IM, Verweij, N, Linneberg, A, Skaaby, T, Doevendans, PA, Cramer, MJ, Van Der Harst, P, Klungel, OH, Dowling, NF, Dominiczak, AF, Kumari, M, Nicolaides, AN, Weikert, C, Boeing, H, Ebrahim, S, Gaunt, TR, Price, JF, Lannfelt, L, Peasey, A, Kubinova, R, Pajak, A, Malyutina, S, Voevoda, MI, Tamosiunas, A, Maitland-van Der Zee, AH, Norman, PE, Hankey, GJ, Bergmann, MM, Hofman, A, Franco, OH, Cooper, J, Palmen, J, Spiering, W, De Jong, PA, Kuh, D, Hardy, R, Uitterlinden, AG, Ikram, MA, Ford, I, Hyppönen, E, Almeida, OP, Wareham, NJ, Khaw, KT, Hamsten, A, Husemoen, LLN, Tjønneland, A, Tolstrup, JS, Rimm, E, Beulens, JWJ, Verschuren, WMM, Onland-Moret, NC, Hofker, MH, Wannamethee, SG, Whincup, PH, Morris, R, Vicente, AM, Watkins, H, Farrall, M, Jukema, JW, Meschia, J, Cupples, LA, Sharp, SJ, Fornage, M, Kooperberg, C, LaCroix, AZ, Dai, JY, Lanktree, MB, Siscovick, DS, Jorgenson, E, Spring, B, Coresh, J, Li, YR, Buxbaum, SG, Schreiner, PJ, Ellison, RC, Tsai, MY, Patel, SR, Redline, S, Johnson, AD, Hoogeveen, RC, Hakonarson, H, Rotter, JI, Boerwinkle, E, De Bakker, PIW, Kivimaki, M, Asselbergs, FW, Sattar, N, Lawlor, DA, Whittaker, J, Smith, GD, Mukamal, K, Psaty, BM, Wilson, JG, Lange, LA, Hamidovic, A, Nordestgaard, BG, Bobak, M, Leon, DA, Langenberg, C, Palmer, TM, Reiner, AP, Keating, BJ, Dudbridge, F & Casas, JP 2014, 'Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data', BMJ, vol. 349, g4164. https://doi.org/10.1136/bmj.g4164

@article{2db530d61c4c42f2ae2cb43bf2d8bfef,

title = "Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data",

author = "Holmes, \{Michael V.\} and Dale, \{Caroline E.\} and Luisa Zuccolo and Silverwood, \{Richard J.\} and Yiran Guo and Zheng Ye and David Prieto-Merino and Abbas Dehghan and Stella Trompet and Andrew Wong and Alana Cavadino and Dagmar Drogan and Sandosh Padmanabhan and Shanshan Li and Ajay Yesupriya and Maarten Leusink and Johan Sundstrom and Hubacek, \{Jaroslav A.\} and Hynek Pikhart and Swerdlow, \{Daniel I.\} and Panayiotou, \{Andrie G.\} and Borinskaya, \{Svetlana A.\} and Chris Finan and Sonia Shah and Kuchenbaecker, \{Karoline B.\} and Tina Shah and Jorgen Engmann and Lasse Folkersen and Per Eriksson and Fulvio Ricceri and Olle Melander and Carlotta Sacerdote and Gamble, \{Dale M.\} and Sruti Rayaprolu and Ross, \{Owen A.\} and Stela McLachlan and Olga Vikhireva and Ivonne Sluijs and Scott, \{Robert A.\} and Vera Adamkova and Leon Flicker and \{Van Bockxmeer\}, \{Frank M.\} and Christine Power and Pedro Marques-Vidal and Tom Meade and Marmot, \{Michael G.\} and Ferro, \{Jose M.\} and Sofia Paulos-Pinheiro and Humphries, \{Steve E.\} and Talmud, \{Philippa J.\} and Leach, \{Irene Mateo\} and Niek Verweij and Allan Linneberg and Tea Skaaby and Doevendans, \{Pieter A.\} and Cramer, \{Maarten J.\} and \{Van Der Harst\}, Pim and Klungel, \{Olaf H.\} and Dowling, \{Nicole F.\} and Dominiczak, \{Anna F.\} and Meena Kumari and Nicolaides, \{Andrew N.\} and Cornelia Weikert and Heiner Boeing and Shah Ebrahim and Gaunt, \{Tom R.\} and Price, \{Jackie F.\} and Lars Lannfelt and Anne Peasey and Ruzena Kubinova and Andrzej Pajak and Sofia Malyutina and Voevoda, \{Mikhail I.\} and Abdonas Tamosiunas and \{Maitland-van Der Zee\}, \{Anke H.\} and Norman, \{Paul E.\} and Hankey, \{Graeme J.\} and Bergmann, \{Manuela M.\} and Albert Hofman and Franco, \{Oscar H.\} and Jackie Cooper and Jutta Palmen and Wilko Spiering and \{De Jong\}, \{Pim A.\} and Diana Kuh and Rebecca Hardy and Uitterlinden, \{Andre G.\} and Ikram, \{M. Arfan\} and Ian Ford and Elina Hypp{\"o}nen and Almeida, \{Osvaldo P.\} and Wareham, \{Nicholas J.\} and Khaw, \{Kay Tee\} and Anders Hamsten and Husemoen, \{Lise Lotte N.\} and Anne Tj{\o}nneland and Tolstrup, \{Janne S.\} and Eric Rimm and Beulens, \{Joline W.J.\} and Verschuren, \{W. M.Monique\} and Onland-Moret, \{N. Charlotte\} and Hofker, \{Marten H.\} and Wannamethee, \{S. Goya\} and Whincup, \{Peter H.\} and Richard Morris and Vicente, \{Astrid M.\} and Hugh Watkins and Martin Farrall and Jukema, \{J. Wouter\} and James Meschia and Cupples, \{L. Adrienne\} and Sharp, \{Stephen J.\} and Myriam Fornage and Charles Kooperberg and LaCroix, \{Andrea Z.\} and Dai, \{James Y.\} and Lanktree, \{Matthew B.\} and Siscovick, \{David S.\} and Eric Jorgenson and Bonnie Spring and Josef Coresh and Li, \{Yun R.\} and Buxbaum, \{Sarah G.\} and Schreiner, \{Pamela J.\} and Ellison, \{R. Curtis\} and Tsai, \{Michael Y.\} and Patel, \{Sanjay R.\} and Susan Redline and Johnson, \{Andrew D.\} and Hoogeveen, \{Ron C.\} and Hakon Hakonarson and Rotter, \{Jerome I.\} and Eric Boerwinkle and \{De Bakker\}, \{Paul I.W.\} and Mika Kivimaki and Asselbergs, \{Folkert W.\} and Naveed Sattar and Lawlor, \{Debbie A.\} and John Whittaker and Smith, \{George Davey\} and Kenneth Mukamal and Psaty, \{Bruce M.\} and Wilson, \{James G.\} and Lange, \{Leslie A.\} and Ajna Hamidovic and Nordestgaard, \{B{\o}rge G.\} and Martin Bobak and Leon, \{David A.\} and Claudia Langenberg and Palmer, \{Tom M.\} and Reiner, \{Alex P.\} and Keating, \{Brendan J.\} and Frank Dudbridge and Casas, \{Juan P.\}",

year = "2014",

month = jul,

day = "10",

doi = "10.1136/bmj.g4164",

language = "English",

volume = "349",

journal = "BMJ",

issn = "0959-8146",

publisher = "BMJ Publishing Group",

}

TY - JOUR

T1 - Association between alcohol and cardiovascular disease

T2 - Mendelian randomisation analysis based on individual participant data

AU - Holmes, Michael V.

AU - Dale, Caroline E.

AU - Zuccolo, Luisa

AU - Silverwood, Richard J.

AU - Guo, Yiran

AU - Ye, Zheng

AU - Prieto-Merino, David

AU - Dehghan, Abbas

AU - Trompet, Stella

AU - Wong, Andrew

AU - Cavadino, Alana

AU - Drogan, Dagmar

AU - Padmanabhan, Sandosh

AU - Li, Shanshan

AU - Yesupriya, Ajay

AU - Leusink, Maarten

AU - Sundstrom, Johan

AU - Hubacek, Jaroslav A.

AU - Pikhart, Hynek

AU - Swerdlow, Daniel I.

AU - Panayiotou, Andrie G.

AU - Borinskaya, Svetlana A.

AU - Finan, Chris

AU - Shah, Sonia

AU - Kuchenbaecker, Karoline B.

AU - Shah, Tina

AU - Engmann, Jorgen

AU - Folkersen, Lasse

AU - Eriksson, Per

AU - Ricceri, Fulvio

AU - Melander, Olle

AU - Sacerdote, Carlotta

AU - Gamble, Dale M.

AU - Rayaprolu, Sruti

AU - Ross, Owen A.

AU - McLachlan, Stela

AU - Vikhireva, Olga

AU - Sluijs, Ivonne

AU - Scott, Robert A.

AU - Adamkova, Vera

AU - Flicker, Leon

AU - Van Bockxmeer, Frank M.

AU - Power, Christine

AU - Marques-Vidal, Pedro

AU - Meade, Tom

AU - Marmot, Michael G.

AU - Ferro, Jose M.

AU - Paulos-Pinheiro, Sofia

AU - Humphries, Steve E.

AU - Talmud, Philippa J.

AU - Leach, Irene Mateo

AU - Verweij, Niek

AU - Linneberg, Allan

AU - Skaaby, Tea

AU - Doevendans, Pieter A.

AU - Cramer, Maarten J.

AU - Van Der Harst, Pim

AU - Klungel, Olaf H.

AU - Dowling, Nicole F.

AU - Dominiczak, Anna F.

AU - Kumari, Meena

AU - Nicolaides, Andrew N.

AU - Weikert, Cornelia

AU - Boeing, Heiner

AU - Ebrahim, Shah

AU - Gaunt, Tom R.

AU - Price, Jackie F.

AU - Lannfelt, Lars

AU - Peasey, Anne

AU - Kubinova, Ruzena

AU - Pajak, Andrzej

AU - Malyutina, Sofia

AU - Voevoda, Mikhail I.

AU - Tamosiunas, Abdonas

AU - Maitland-van Der Zee, Anke H.

AU - Norman, Paul E.

AU - Hankey, Graeme J.

AU - Bergmann, Manuela M.

AU - Hofman, Albert

AU - Franco, Oscar H.

AU - Cooper, Jackie

AU - Palmen, Jutta

AU - Spiering, Wilko

AU - De Jong, Pim A.

AU - Kuh, Diana

AU - Hardy, Rebecca

AU - Uitterlinden, Andre G.

AU - Ikram, M. Arfan

AU - Ford, Ian

AU - Hyppönen, Elina

AU - Almeida, Osvaldo P.

AU - Wareham, Nicholas J.

AU - Khaw, Kay Tee

AU - Hamsten, Anders

AU - Husemoen, Lise Lotte N.

AU - Tjønneland, Anne

AU - Tolstrup, Janne S.

AU - Rimm, Eric

AU - Beulens, Joline W.J.

AU - Verschuren, W. M.Monique

AU - Onland-Moret, N. Charlotte

AU - Hofker, Marten H.

AU - Wannamethee, S. Goya

AU - Whincup, Peter H.

AU - Morris, Richard

AU - Vicente, Astrid M.

AU - Watkins, Hugh

AU - Farrall, Martin

AU - Jukema, J. Wouter

AU - Meschia, James

AU - Cupples, L. Adrienne

AU - Sharp, Stephen J.

AU - Fornage, Myriam

AU - Kooperberg, Charles

AU - LaCroix, Andrea Z.

AU - Dai, James Y.

AU - Lanktree, Matthew B.

AU - Siscovick, David S.

AU - Jorgenson, Eric

AU - Spring, Bonnie

AU - Coresh, Josef

AU - Li, Yun R.

AU - Buxbaum, Sarah G.

AU - Schreiner, Pamela J.

AU - Ellison, R. Curtis

AU - Tsai, Michael Y.

AU - Patel, Sanjay R.

AU - Redline, Susan

AU - Johnson, Andrew D.

AU - Hoogeveen, Ron C.

AU - Hakonarson, Hakon

AU - Rotter, Jerome I.

AU - Boerwinkle, Eric

AU - De Bakker, Paul I.W.

AU - Kivimaki, Mika

AU - Asselbergs, Folkert W.

AU - Sattar, Naveed

AU - Lawlor, Debbie A.

AU - Whittaker, John

AU - Smith, George Davey

AU - Mukamal, Kenneth

AU - Psaty, Bruce M.

AU - Wilson, James G.

AU - Lange, Leslie A.

AU - Hamidovic, Ajna

AU - Nordestgaard, Børge G.

AU - Bobak, Martin

AU - Leon, David A.

AU - Langenberg, Claudia

AU - Palmer, Tom M.

AU - Reiner, Alex P.

AU - Keating, Brendan J.

AU - Dudbridge, Frank

AU - Casas, Juan P.

PY - 2014/7/10

Y1 - 2014/7/10

UR - https://www.scopus.com/pages/publications/84904064886

UR - https://www.scopus.com/pages/publications/84904064886#tab=citedBy

U2 - 10.1136/bmj.g4164

DO - 10.1136/bmj.g4164

M3 - Article

C2 - 25011450

AN - SCOPUS:84904064886

SN - 0959-8146

VL - 349

JO - BMJ

JF - BMJ

M1 - g4164

ER -

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

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