Attentional networks and cingulum bundle in chronic schizophrenia

Paul G. Nestor; Marek Kubicki; Kevin M. Spencer; Margaret Niznikiewicz; Robert W. McCarley; Martha E. Shenton

doi:10.1016/j.schres.2006.10.005

Attentional networks and cingulum bundle in chronic schizophrenia

Paul G. Nestor
, Marek Kubicki
, Kevin M. Spencer
, Margaret Niznikiewicz
, Robert W. McCarley
, Martha E. Shenton

Psychology

VA Medical Center
Brigham and Women’s Hospital

Research output: Contribution to journal › Article › peer-review

Abstract

Thirty patients with chronic schizophrenia and 30 age-matched controls performed the Attention Network Test (ANT). A subset of the patient group (n = 18) also had available magnetic resonance diffusion tensor imaging (DTI) measures of the cingulum bundle (CB) fractional anisotropy and volume. The patients showed a significantly different pattern of ANT performance, characterized primarily by decreased alerting efficiency. In addition, left CB fractional anisotropy correlated significantly with orienting of attention. Smaller right CB volume also correlated with reduced alertness, but not when covarying for medication and illness duration.

Original language	English
Pages (from-to)	308-315
Number of pages	8
Journal	Schizophrenia Research
Volume	90
Issue number	1-3
DOIs	https://doi.org/10.1016/j.schres.2006.10.005
State	Published - Feb 2007

ASJC Scopus Subject Areas

Psychiatry and Mental health
Biological Psychiatry

Keywords

Attention
Cingulum bundle
Schizophrenia

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10.1016/j.schres.2006.10.005

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title = "Attentional networks and cingulum bundle in chronic schizophrenia",

abstract = "Thirty patients with chronic schizophrenia and 30 age-matched controls performed the Attention Network Test (ANT). A subset of the patient group (n = 18) also had available magnetic resonance diffusion tensor imaging (DTI) measures of the cingulum bundle (CB) fractional anisotropy and volume. The patients showed a significantly different pattern of ANT performance, characterized primarily by decreased alerting efficiency. In addition, left CB fractional anisotropy correlated significantly with orienting of attention. Smaller right CB volume also correlated with reduced alertness, but not when covarying for medication and illness duration.",

keywords = "Attention, Cingulum bundle, Schizophrenia",

author = "Nestor, \{Paul G.\} and Marek Kubicki and Spencer, \{Kevin M.\} and Margaret Niznikiewicz and McCarley, \{Robert W.\} and Shenton, \{Martha E.\}",

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doi = "10.1016/j.schres.2006.10.005",

language = "English",

volume = "90",

pages = "308--315",

journal = "Schizophrenia Research",

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AU - Nestor, Paul G.

AU - Kubicki, Marek

AU - Spencer, Kevin M.

AU - Niznikiewicz, Margaret

AU - McCarley, Robert W.

AU - Shenton, Martha E.

PY - 2007/2

Y1 - 2007/2

N2 - Thirty patients with chronic schizophrenia and 30 age-matched controls performed the Attention Network Test (ANT). A subset of the patient group (n = 18) also had available magnetic resonance diffusion tensor imaging (DTI) measures of the cingulum bundle (CB) fractional anisotropy and volume. The patients showed a significantly different pattern of ANT performance, characterized primarily by decreased alerting efficiency. In addition, left CB fractional anisotropy correlated significantly with orienting of attention. Smaller right CB volume also correlated with reduced alertness, but not when covarying for medication and illness duration.

AB - Thirty patients with chronic schizophrenia and 30 age-matched controls performed the Attention Network Test (ANT). A subset of the patient group (n = 18) also had available magnetic resonance diffusion tensor imaging (DTI) measures of the cingulum bundle (CB) fractional anisotropy and volume. The patients showed a significantly different pattern of ANT performance, characterized primarily by decreased alerting efficiency. In addition, left CB fractional anisotropy correlated significantly with orienting of attention. Smaller right CB volume also correlated with reduced alertness, but not when covarying for medication and illness duration.

KW - Attention

KW - Cingulum bundle

KW - Schizophrenia

UR - https://www.scopus.com/pages/publications/33846697598

UR - https://www.scopus.com/pages/publications/33846697598#tab=citedBy

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AN - SCOPUS:33846697598

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EP - 315

JO - Schizophrenia Research

JF - Schizophrenia Research

IS - 1-3

ER -

Attentional networks and cingulum bundle in chronic schizophrenia

Abstract

ASJC Scopus Subject Areas

Keywords

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