Babesia divergens host cell egress is mediated by essential and druggable kinases and proteases

Brendan Elsworth; Caroline D. Keroack; Yasaman Rezvani; Aditya S. Paul; Keare A. Barazorda; Niel C. Bauer; Jacob A. Tennessen; Samantha A. Sack; Cristina K. Moreira; Marc Jan Gubbels; Marvin J. Meyers; Kourosh Zarringhalam; Manoj T. Duraisingh

doi:10.1038/s41564-025-02238-7

Babesia divergens host cell egress is mediated by essential and druggable kinases and proteases

Brendan Elsworth
, Caroline D. Keroack
, Yasaman Rezvani
, Aditya S. Paul
, Keare A. Barazorda
, Niel C. Bauer
, Jacob A. Tennessen
, Samantha A. Sack
, Cristina K. Moreira
, Marc Jan Gubbels
, Marvin J. Meyers
, Kourosh Zarringhalam
, Manoj T. Duraisingh

Mathematics

Harvard University
United States Food and Drug Administration
University of Massachusetts Boston
Boston College
Saint Louis University

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	492-506
Number of pages	15
Journal	Nature Microbiology
Volume	11
Issue number	2
DOIs	https://doi.org/10.1038/s41564-025-02238-7
State	Published - Feb 2026

ASJC Scopus Subject Areas

Microbiology
Immunology
Applied Microbiology and Biotechnology
Genetics
Microbiology (medical)
Cell Biology

Access to Document

10.1038/s41564-025-02238-7

Cite this

Elsworth, B., Keroack, C. D., Rezvani, Y., Paul, A. S., Barazorda, K. A., Bauer, N. C., Tennessen, J. A., Sack, S. A., Moreira, C. K., Gubbels, M. J., Meyers, M. J., Zarringhalam, K., & Duraisingh, M. T. (2026). Babesia divergens host cell egress is mediated by essential and druggable kinases and proteases. Nature Microbiology, 11(2), 492-506. https://doi.org/10.1038/s41564-025-02238-7

@article{be403d27d1984cbcb6c377ce197693f1,

title = "Babesia divergens host cell egress is mediated by essential and druggable kinases and proteases",

author = "Brendan Elsworth and Keroack, \{Caroline D.\} and Yasaman Rezvani and Paul, \{Aditya S.\} and Barazorda, \{Keare A.\} and Bauer, \{Niel C.\} and Tennessen, \{Jacob A.\} and Sack, \{Samantha A.\} and Moreira, \{Cristina K.\} and Gubbels, \{Marc Jan\} and Meyers, \{Marvin J.\} and Kourosh Zarringhalam and Duraisingh, \{Manoj T.\}",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2026.",

year = "2026",

month = feb,

doi = "10.1038/s41564-025-02238-7",

language = "English",

volume = "11",

pages = "492--506",

journal = "Nature Microbiology",

issn = "2058-5276",

publisher = "Nature Research",

number = "2",

}

TY - JOUR

T1 - Babesia divergens host cell egress is mediated by essential and druggable kinases and proteases

AU - Elsworth, Brendan

AU - Keroack, Caroline D.

AU - Rezvani, Yasaman

AU - Paul, Aditya S.

AU - Barazorda, Keare A.

AU - Bauer, Niel C.

AU - Tennessen, Jacob A.

AU - Sack, Samantha A.

AU - Moreira, Cristina K.

AU - Gubbels, Marc Jan

AU - Meyers, Marvin J.

AU - Zarringhalam, Kourosh

AU - Duraisingh, Manoj T.

PY - 2026/2

Y1 - 2026/2

UR - https://www.scopus.com/pages/publications/105028875065

UR - https://www.scopus.com/pages/publications/105028875065#tab=citedBy

U2 - 10.1038/s41564-025-02238-7

DO - 10.1038/s41564-025-02238-7

M3 - Article

C2 - 41593365

AN - SCOPUS:105028875065

SN - 2058-5276

VL - 11

SP - 492

EP - 506

JO - Nature Microbiology

JF - Nature Microbiology

IS - 2

ER -

Babesia divergens host cell egress is mediated by essential and druggable kinases and proteases

ASJC Scopus Subject Areas

Access to Document

Other files and links

Fingerprint

Cite this