BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer

  • Gonghong Yan
  • , Augustin Luna
  • , Heping Wang
  • , Behnaz Bozorgui
  • , Xubin Li
  • , Maga Sanchez
  • , Zeynep Dereli
  • , Nermin Kahraman
  • , Goknur Kara
  • , Xiaohua Chen
  • , Caishang Zheng
  • , Daniel McGrail
  • , Nidhi Sahni
  • , Yiling Lu
  • , Ozgun Babur
  • , Murat Cokol
  • , Bora Lim
  • , Bulent Ozpolat
  • , Chris Sander
  • , Gordon B. Mills
  • Anil Korkut

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number111304
JournalCell Reports
Volume40
Issue number11
DOIs
StatePublished - Sep 13 2022

ASJC Scopus Subject Areas

  • General Biochemistry,Genetics and Molecular Biology

Keywords

  • adaptive responses
  • apoptosis
  • bioinformatics
  • BRD4
  • combination therapy
  • CP: Cancer
  • drug resistance
  • fatty acid pathway
  • lipids
  • MCL1
  • network models

Fingerprint

Dive into the research topics of 'BET inhibition induces vulnerability to MCL1 targeting through upregulation of fatty acid synthesis pathway in breast cancer'. Together they form a unique fingerprint.

Cite this