Binding of α,α-disubstituted amino acids to arginase suggests new avenues for inhibitor design

Monica Ilies; Luigi Di Costanzo; Daniel P. Dowling; Katherine J. Thorn; David W. Christianson

doi:10.1021/jm200443b

Binding of α,α-disubstituted amino acids to arginase suggests new avenues for inhibitor design

Monica Ilies
, Luigi Di Costanzo
, Daniel P. Dowling
, Katherine J. Thorn
, David W. Christianson

Chemistry

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	5432-5443
Number of pages	12
Journal	Journal of Medicinal Chemistry
Volume	54
Issue number	15
DOIs	https://doi.org/10.1021/jm200443b
State	Published - Aug 11 2011

ASJC Scopus Subject Areas

Molecular Medicine
Drug Discovery

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10.1021/jm200443b

Cite this

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title = "Binding of α,α-disubstituted amino acids to arginase suggests new avenues for inhibitor design",

author = "Monica Ilies and \{Di Costanzo\}, Luigi and Dowling, \{Daniel P.\} and Thorn, \{Katherine J.\} and Christianson, \{David W.\}",

year = "2011",

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day = "11",

doi = "10.1021/jm200443b",

language = "English",

volume = "54",

pages = "5432--5443",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

number = "15",

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T1 - Binding of α,α-disubstituted amino acids to arginase suggests new avenues for inhibitor design

AU - Ilies, Monica

AU - Di Costanzo, Luigi

AU - Dowling, Daniel P.

AU - Thorn, Katherine J.

AU - Christianson, David W.

PY - 2011/8/11

Y1 - 2011/8/11

UR - https://www.scopus.com/pages/publications/79961238056

UR - https://www.scopus.com/pages/publications/79961238056#tab=citedBy

U2 - 10.1021/jm200443b

DO - 10.1021/jm200443b

M3 - Article

C2 - 21728378

AN - SCOPUS:79961238056

SN - 0022-2623

VL - 54

SP - 5432

EP - 5443

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 15

ER -

Binding of α,α-disubstituted amino acids to arginase suggests new avenues for inhibitor design

ASJC Scopus Subject Areas

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