Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer

Carman Man Chung Li; Alyssa Cordes; Michael U.J. Oliphant; S. Aidan Quinn; Mayura Thomas; Laura M. Selfors; Francesca Silvestri; Nomeda Girnius; Gianmarco Rinaldi; Jason J. Zoeller; Hana Shapiro; Christina Tsiobikas; Kushali P. Gupta; Shailja Pathania; Aviv Regev; Cigall Kadoch; Senthil K. Muthuswamy; Joan S. Brugge

doi:10.1038/s41588-024-01958-6

Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer

Carman Man Chung Li
, Alyssa Cordes
, Michael U.J. Oliphant
, S. Aidan Quinn
, Mayura Thomas
, Laura M. Selfors
, Francesca Silvestri
, Nomeda Girnius
, Gianmarco Rinaldi
, Jason J. Zoeller
, Hana Shapiro
, Christina Tsiobikas
, Kushali P. Gupta
, Shailja Pathania
, Aviv Regev
, Cigall Kadoch
, Senthil K. Muthuswamy
, Joan S. Brugge

Biology

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	5496
Pages (from-to)	2763-2775
Number of pages	13
Journal	Nature Genetics
Volume	56
Issue number	12
DOIs	https://doi.org/10.1038/s41588-024-01958-6
State	Published - Dec 2024

ASJC Scopus Subject Areas

Genetics

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10.1038/s41588-024-01958-6

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Li, C. M. C., Cordes, A., Oliphant, M. U. J., Quinn, S. A., Thomas, M., Selfors, L. M., Silvestri, F., Girnius, N., Rinaldi, G., Zoeller, J. J., Shapiro, H., Tsiobikas, C., Gupta, K. P., Pathania, S., Regev, A., Kadoch, C., Muthuswamy, S. K., & Brugge, J. S. (2024). Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer. Nature Genetics, 56(12), 2763-2775. Article 5496. https://doi.org/10.1038/s41588-024-01958-6

Li, CMC, Cordes, A, Oliphant, MUJ, Quinn, SA, Thomas, M, Selfors, LM, Silvestri, F, Girnius, N, Rinaldi, G, Zoeller, JJ, Shapiro, H, Tsiobikas, C, Gupta, KP, Pathania, S, Regev, A, Kadoch, C, Muthuswamy, SK & Brugge, JS 2024, 'Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer', Nature Genetics, vol. 56, no. 12, 5496, pp. 2763-2775. https://doi.org/10.1038/s41588-024-01958-6

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title = "Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer",

author = "Li, \{Carman Man Chung\} and Alyssa Cordes and Oliphant, \{Michael U.J.\} and Quinn, \{S. Aidan\} and Mayura Thomas and Selfors, \{Laura M.\} and Francesca Silvestri and Nomeda Girnius and Gianmarco Rinaldi and Zoeller, \{Jason J.\} and Hana Shapiro and Christina Tsiobikas and Gupta, \{Kushali P.\} and Shailja Pathania and Aviv Regev and Cigall Kadoch and Muthuswamy, \{Senthil K.\} and Brugge, \{Joan S.\}",

note = "Publisher Copyright: {\textcopyright} The Author(s), under exclusive licence to Springer Nature America, Inc. 2024.",

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AU - Li, Carman Man Chung

AU - Cordes, Alyssa

AU - Oliphant, Michael U.J.

AU - Quinn, S. Aidan

AU - Thomas, Mayura

AU - Selfors, Laura M.

AU - Silvestri, Francesca

AU - Girnius, Nomeda

AU - Rinaldi, Gianmarco

AU - Zoeller, Jason J.

AU - Shapiro, Hana

AU - Tsiobikas, Christina

AU - Gupta, Kushali P.

AU - Pathania, Shailja

AU - Regev, Aviv

AU - Kadoch, Cigall

AU - Muthuswamy, Senthil K.

AU - Brugge, Joan S.

PY - 2024/12

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JO - Nature Genetics

JF - Nature Genetics

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Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer

ASJC Scopus Subject Areas

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