BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model

Ye He; Joshua Rivera; Miklos Diossy; Haohui Duan; Christian Bowman-Colin; Rachel Reed; Rebecca Jennings; Jesse Novak; Stevenson V. Tran; Elizabeth F. Cohen; David Szuts; Anita Giobbie-Hurder; Roderick T. Bronson; Adam J. Bass; Sabina Signoretti; Zoltan Szallasi; David M. Livingston; Shailja Pathania

doi:10.1073/pnas.2108421118

BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model

Ye He
, Joshua Rivera
, Miklos Diossy
, Haohui Duan
, Christian Bowman-Colin
, Rachel Reed
, Rebecca Jennings
, Jesse Novak
, Stevenson V. Tran
, Elizabeth F. Cohen
, David Szuts
, Anita Giobbie-Hurder
, Roderick T. Bronson
, Adam J. Bass
, Sabina Signoretti
, Zoltan Szallasi
, David M. Livingston
, Shailja Pathania

Biology

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	e2108421118
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	118
Issue number	41
DOIs	https://doi.org/10.1073/pnas.2108421118
State	Published - Oct 12 2021

ASJC Scopus Subject Areas

General

Keywords

BRCA1
Haploinsufficiency
Mouse model
Replication stress

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10.1073/pnas.2108421118

Cite this

He, Y., Rivera, J., Diossy, M., Duan, H., Bowman-Colin, C., Reed, R., Jennings, R., Novak, J., Tran, S. V., Cohen, E. F., Szuts, D., Giobbie-Hurder, A., Bronson, R. T., Bass, A. J., Signoretti, S., Szallasi, Z., Livingston, D. M., & Pathania, S. (2021). BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model. Proceedings of the National Academy of Sciences of the United States of America, 118(41), Article e2108421118. https://doi.org/10.1073/pnas.2108421118

He, Y, Rivera, J, Diossy, M, Duan, H, Bowman-Colin, C, Reed, R, Jennings, R, Novak, J, Tran, SV, Cohen, EF, Szuts, D, Giobbie-Hurder, A, Bronson, RT, Bass, AJ, Signoretti, S, Szallasi, Z, Livingston, DM & Pathania, S 2021, 'BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 41, e2108421118. https://doi.org/10.1073/pnas.2108421118

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title = "BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model",

keywords = "BRCA1, Haploinsufficiency, Mouse model, Replication stress",

author = "Ye He and Joshua Rivera and Miklos Diossy and Haohui Duan and Christian Bowman-Colin and Rachel Reed and Rebecca Jennings and Jesse Novak and Tran, \{Stevenson V.\} and Cohen, \{Elizabeth F.\} and David Szuts and Anita Giobbie-Hurder and Bronson, \{Roderick T.\} and Bass, \{Adam J.\} and Sabina Signoretti and Zoltan Szallasi and Livingston, \{David M.\} and Shailja Pathania",

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doi = "10.1073/pnas.2108421118",

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T1 - BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model

AU - He, Ye

AU - Rivera, Joshua

AU - Diossy, Miklos

AU - Duan, Haohui

AU - Bowman-Colin, Christian

AU - Reed, Rachel

AU - Jennings, Rebecca

AU - Novak, Jesse

AU - Tran, Stevenson V.

AU - Cohen, Elizabeth F.

AU - Szuts, David

AU - Giobbie-Hurder, Anita

AU - Bronson, Roderick T.

AU - Bass, Adam J.

AU - Signoretti, Sabina

AU - Szallasi, Zoltan

AU - Livingston, David M.

AU - Pathania, Shailja

PY - 2021/10/12

Y1 - 2021/10/12

KW - BRCA1

KW - Haploinsufficiency

KW - Mouse model

KW - Replication stress

UR - https://www.scopus.com/pages/publications/85116574736

UR - https://www.scopus.com/pages/publications/85116574736#tab=citedBy

U2 - 10.1073/pnas.2108421118

DO - 10.1073/pnas.2108421118

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AN - SCOPUS:85116574736

SN - 0027-8424

VL - 118

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

IS - 41

M1 - e2108421118

ER -

BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model

ASJC Scopus Subject Areas

Keywords

Access to Document

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