Combining metformin therapy with caloric restriction for the management of type 2 diabetes and nonalcoholic fatty liver disease in obese rats

Melissa A. Linden; Kristi T. Lopez; Justin A. Fletcher; E. Matthew Morris; Grace M. Meers; Sameer Siddique; M. Harold Laughlin; James R. Sowers; John P. Thyfault; Jamal A. Ibdah; R. Scott Rector

doi:10.1139/apnm-2015-0236

Combining metformin therapy with caloric restriction for the management of type 2 diabetes and nonalcoholic fatty liver disease in obese rats

Melissa A. Linden
, Kristi T. Lopez
, Justin A. Fletcher
, E. Matthew Morris
, Grace M. Meers
, Sameer Siddique
, M. Harold Laughlin
, James R. Sowers
, John P. Thyfault
, Jamal A. Ibdah
, R. Scott Rector

Exercise & Health Science

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	1038-1047
Number of pages	10
Journal	Applied Physiology, Nutrition and Metabolism
Volume	40
Issue number	10
DOIs	https://doi.org/10.1139/apnm-2015-0236
State	Published - Sep 22 2015

ASJC Scopus Subject Areas

Endocrinology, Diabetes and Metabolism
Physiology
Nutrition and Dietetics
Physiology (medical)

Keywords

Caloric restriction
De novo lipogenesis
Hepatic steatosis
Metformin
Mitochondrial function
Nonalcoholic fatty liver disease

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10.1139/apnm-2015-0236

Cite this

Linden, M. A., Lopez, K. T., Fletcher, J. A., Morris, E. M., Meers, G. M., Siddique, S., Laughlin, M. H., Sowers, J. R., Thyfault, J. P., Ibdah, J. A., & Rector, R. S. (2015). Combining metformin therapy with caloric restriction for the management of type 2 diabetes and nonalcoholic fatty liver disease in obese rats. Applied Physiology, Nutrition and Metabolism, 40(10), 1038-1047. https://doi.org/10.1139/apnm-2015-0236

Combining metformin therapy with caloric restriction for the management of type 2 diabetes and nonalcoholic fatty liver disease in obese rats. / Linden, Melissa A.; Lopez, Kristi T.; Fletcher, Justin A. et al.
In: Applied Physiology, Nutrition and Metabolism, Vol. 40, No. 10, 22.09.2015, p. 1038-1047.

Research output: Contribution to journal › Article › peer-review

Linden, MA, Lopez, KT, Fletcher, JA, Morris, EM, Meers, GM, Siddique, S, Laughlin, MH, Sowers, JR, Thyfault, JP, Ibdah, JA & Rector, RS 2015, 'Combining metformin therapy with caloric restriction for the management of type 2 diabetes and nonalcoholic fatty liver disease in obese rats', Applied Physiology, Nutrition and Metabolism, vol. 40, no. 10, pp. 1038-1047. https://doi.org/10.1139/apnm-2015-0236

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AU - Linden, Melissa A.

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AU - Morris, E. Matthew

AU - Meers, Grace M.

AU - Siddique, Sameer

AU - Laughlin, M. Harold

AU - Sowers, James R.

AU - Thyfault, John P.

AU - Ibdah, Jamal A.

AU - Rector, R. Scott

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KW - De novo lipogenesis

KW - Hepatic steatosis

KW - Metformin

KW - Mitochondrial function

KW - Nonalcoholic fatty liver disease

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Combining metformin therapy with caloric restriction for the management of type 2 diabetes and nonalcoholic fatty liver disease in obese rats

ASJC Scopus Subject Areas

Keywords

Access to Document

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