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Deprotection and cleavage of peptides bound to Merrifield resin by stable dimethyl ether–poly(hydrogen fluoride) (DMEPHF) complex. A new and convenient reagent for peptide chemistry

  • University of Southern California

Research output: Contribution to journal › Article › peer-review

Abstract

The newly developed stable DMEPHF (1/15) complex was found to be a highly effective reagent for the cleavage of peptides from Merrifield resins; ease of handling and its simple, complete removal from the reaction mixture make the reagent system a very useful HF equivalent for applications in solid-phase peptide synthesis.

Original languageEnglish
Pages (from-to)2882-2883
Number of pages2
JournalChemical Communications
Volume2
Issue number23
DOIs
StatePublished - 2002

ASJC Scopus Subject Areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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