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Effects of Tai Chi on beta endorphin and inflammatory markers in older adults with chronic pain: an exploratory study

  • Tongjian You
  • , Elisa F. Ogawa
  • , Saurja Thapa
  • , Yurun Cai
  • , Gloria Y. Yeh
  • , Peter M. Wayne
  • , Ling Shi
  • , Suzanne G. Leveille
  • University of Massachusetts Boston
  • Department of Veterans Affairs
  • Beth Israel Deaconess Medical Center
  • Harvard University
  • Brigham and Women’s Hospital

Research output: Contribution to journal › Article › peer-review

Abstract

The purpose of this exploratory study was to examine the effects of Tai Chi on blood levels of beta endorphin (β-endorphin) and inflammatory markers in older adults with chronic pain. Forty community-dwelling older adults with chronic pain were randomized to Tai Chi or light physical exercise, and each offered twice weekly for 12 weeks. Following the 12-week intervention, neither Tai Chi nor light physical exercise changed levels of β-endorphin and inflammatory markers. However, in older adults who completed 70% or more classes, Tai Chi significantly lowered levels of β-endorphin (p < 0.05), whereas light physical exercise did not change levels of β-endorphin. The results suggest that Tai Chi may reduce levels of β-endorphin in older adults with chronic pain. Future studies are needed to better understand the role of the opioid analgesic system and immune system in regulating pain with aging and the long-term effects of Tai Chi on pain-related biomarkers.

Original languageEnglish
Pages (from-to)1389-1392
Number of pages4
JournalAging Clinical and Experimental Research
Volume32
Issue number7
DOIs
StatePublished - Jul 1 2020

ASJC Scopus Subject Areas

  • Aging
  • Geriatrics and Gerontology

Keywords

  • Beta endorphin
  • Chronic pain
  • Inflammation
  • Older adults
  • Tai Chi

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