Enabling point of care optical diagnostics and treatment of oral lesions in resource-limited settings: preclinical development and evaluation of a low-cost theranostic intraoral device for image-guided photodynamic therapy

Shakir Khan; Bofan Song; Mohammad Ahsan Saad; Danshyl Boodhoo; Sergio Farias; Jonathan M. Trzcinski; Shaobai Li; Lothar Lilge; Brian W. Pogue; Rongguang Liang; Tayyaba Hasan; Jonathan P. Celli

doi:10.1117/1.BIOS.2.4.042305

Enabling point of care optical diagnostics and treatment of oral lesions in resource-limited settings: preclinical development and evaluation of a low-cost theranostic intraoral device for image-guided photodynamic therapy

Shakir Khan
, Bofan Song
, Mohammad Ahsan Saad
, Danshyl Boodhoo
, Sergio Farias
, Jonathan M. Trzcinski
, Shaobai Li
, Lothar Lilge
, Brian W. Pogue
, Rongguang Liang
, Tayyaba Hasan
, Jonathan P. Celli

Physics

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	042305
Journal	Biophotonics Discovery
Volume	2
Issue number	4
DOIs	https://doi.org/10.1117/1.BIOS.2.4.042305
State	Published - Oct 1 2025

ASJC Scopus Subject Areas

General Biochemistry,Genetics and Molecular Biology
Medicine (miscellaneous)
Radiology Nuclear Medicine and imaging
Biomedical Engineering
Artificial Intelligence

Keywords

5-aminolevulinic acid
intraoral imaging
low- to middle-income countries
oral cancer and oral potentially malignant lesions
photodynamic therapy
smartphone

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10.1117/1.BIOS.2.4.042305

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Khan, S., Song, B., Saad, M. A., Boodhoo, D., Farias, S., Trzcinski, J. M., Li, S., Lilge, L., Pogue, B. W., Liang, R., Hasan, T., & Celli, J. P. (2025). Enabling point of care optical diagnostics and treatment of oral lesions in resource-limited settings: preclinical development and evaluation of a low-cost theranostic intraoral device for image-guided photodynamic therapy. Biophotonics Discovery, 2(4), Article 042305. https://doi.org/10.1117/1.BIOS.2.4.042305

Enabling point of care optical diagnostics and treatment of oral lesions in resource-limited settings: preclinical development and evaluation of a low-cost theranostic intraoral device for image-guided photodynamic therapy. / Khan, Shakir; Song, Bofan; Saad, Mohammad Ahsan et al.
In: Biophotonics Discovery, Vol. 2, No. 4, 042305, 01.10.2025.

Research output: Contribution to journal › Article › peer-review

Khan, S, Song, B, Saad, MA, Boodhoo, D, Farias, S, Trzcinski, JM, Li, S, Lilge, L, Pogue, BW, Liang, R, Hasan, T & Celli, JP 2025, 'Enabling point of care optical diagnostics and treatment of oral lesions in resource-limited settings: preclinical development and evaluation of a low-cost theranostic intraoral device for image-guided photodynamic therapy', Biophotonics Discovery, vol. 2, no. 4, 042305. https://doi.org/10.1117/1.BIOS.2.4.042305

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KW - low- to middle-income countries

KW - oral cancer and oral potentially malignant lesions

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Enabling point of care optical diagnostics and treatment of oral lesions in resource-limited settings: preclinical development and evaluation of a low-cost theranostic intraoral device for image-guided photodynamic therapy

ASJC Scopus Subject Areas

Keywords

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