Fluorous Mixture Synthesis (FMS) of Drug-like Molecules and Enantiomers, Stereoisomers, and Analogues of Natural Products

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish
Title of host publicationFluorine in Medicinal Chemistry and Chemical Biology
PublisherJohn Wiley & Sons, Ltd
Pages335-359
Number of pages25
ISBN (Print)9781405167208
DOIs
StatePublished - Apr 21 2009

ASJC Scopus Subject Areas

  • General Chemistry
  • General Pharmacology, Toxicology and Pharmaceutics
  • General Biochemistry,Genetics and Molecular Biology

Keywords

  • Fluorous Mixture Synthesis (FMS) of drug-like molecules and enantiomers, stereoisomers, and analogues of natural products
  • Fluorous mixture synthesis concept
  • FMS of 16 tecomanine-like compounds
  • FMS of natural products and drug-like compounds and libraries
  • Natural product analogues and drug-like compounds - commonly prepared by solution-phase synthesis
  • Natural products and synthetic drug-like compounds
  • Quantitative structure - activity relationship (QSAR) studies
  • Quasi-racemic FMS
  • Tecomanine-like compound synthesis

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