Free radical-based annulation of alkenes yielding fused cycloheptanones

Wei Zhang; Ye Hua; Garrett Hoge; Paul Dowd

doi:10.1016/S0040-4039(00)76687-1

Free radical-based annulation of alkenes yielding fused cycloheptanones

Wei Zhang
, Ye Hua
, Garrett Hoge
, Paul Dowd

Chemistry

University of Pittsburgh

Research output: Contribution to journal › Article › peer-review

Abstract

Stereospecific annulation of cyclic alkenes for the preparation of cis-fused seven-membered ring systems was accomplished by sequential [2 + 2] cycloaddition, exo-allylation, hydrohalogenation, and free radical ring expansion. The new strategy extends our recently developed cyclobutanone-based ring expansion reactions.

Original language	English
Pages (from-to)	3865-3868
Number of pages	4
Journal	Tetrahedron Letters
Volume	35
Issue number	23
DOIs	https://doi.org/10.1016/S0040-4039(00)76687-1
State	Published - Jun 6 1994

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)76687-1

Cite this

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title = "Free radical-based annulation of alkenes yielding fused cycloheptanones",

abstract = "Stereospecific annulation of cyclic alkenes for the preparation of cis-fused seven-membered ring systems was accomplished by sequential [2 + 2] cycloaddition, exo-allylation, hydrohalogenation, and free radical ring expansion. The new strategy extends our recently developed cyclobutanone-based ring expansion reactions.",

author = "Wei Zhang and Ye Hua and Garrett Hoge and Paul Dowd",

year = "1994",

month = jun,

day = "6",

doi = "10.1016/S0040-4039(00)76687-1",

language = "English",

volume = "35",

pages = "3865--3868",

journal = "Tetrahedron Letters",

issn = "0040-4039",

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T1 - Free radical-based annulation of alkenes yielding fused cycloheptanones

AU - Zhang, Wei

AU - Hua, Ye

AU - Hoge, Garrett

AU - Dowd, Paul

PY - 1994/6/6

Y1 - 1994/6/6

N2 - Stereospecific annulation of cyclic alkenes for the preparation of cis-fused seven-membered ring systems was accomplished by sequential [2 + 2] cycloaddition, exo-allylation, hydrohalogenation, and free radical ring expansion. The new strategy extends our recently developed cyclobutanone-based ring expansion reactions.

AB - Stereospecific annulation of cyclic alkenes for the preparation of cis-fused seven-membered ring systems was accomplished by sequential [2 + 2] cycloaddition, exo-allylation, hydrohalogenation, and free radical ring expansion. The new strategy extends our recently developed cyclobutanone-based ring expansion reactions.

UR - https://www.scopus.com/pages/publications/0028310284

UR - https://www.scopus.com/pages/publications/0028310284#tab=citedBy

U2 - 10.1016/S0040-4039(00)76687-1

DO - 10.1016/S0040-4039(00)76687-1

M3 - Article

AN - SCOPUS:0028310284

SN - 0040-4039

VL - 35

SP - 3865

EP - 3868

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 23

ER -

Free radical-based annulation of alkenes yielding fused cycloheptanones

Abstract

ASJC Scopus Subject Areas

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