Ga(ClO 4) 3-catalyzed synthesis of quinoxalines by cycloaddition of α-hydroxyketones and o-phenylenediamines

Fan Pan; Tang Ming Chen; Jia Jia Cao; Jian Ping Zou; Wei Zhang

doi:10.1016/j.tetlet.2012.02.113

Ga(ClO ₄) ₃-catalyzed synthesis of quinoxalines by cycloaddition of α-hydroxyketones and o-phenylenediamines

Fan Pan
, Tang Ming Chen
, Jia Jia Cao
, Jian Ping Zou
, Wei Zhang

Chemistry

Soochow University

Research output: Contribution to journal › Article › peer-review

Abstract

A new approach for the synthesis of 2-substituted quinoxalines by Ga(ClO ₄) ₃-catalyzed cycloaddition of α- hydroxyketones and o-phenylenediamines is introduced. The reaction is catalyzed by 10 mol % of Ga(ClO ₄) ₃ in EtOH at room temperature. It is performed under simple and mild conditions to afford the product in good yield.

Original language	English
Pages (from-to)	2508-2510
Number of pages	3
Journal	Tetrahedron Letters
Volume	53
Issue number	20
DOIs	https://doi.org/10.1016/j.tetlet.2012.02.113
State	Published - May 16 2012

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

Keywords

α-Hydroxyketones
Cycloaddition
Gallium perchlorate
o-Phenylenediamines
Quinoxalines

Access to Document

10.1016/j.tetlet.2012.02.113

Cite this

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title = "Ga(ClO 4) 3-catalyzed synthesis of quinoxalines by cycloaddition of α-hydroxyketones and o-phenylenediamines",

abstract = "A new approach for the synthesis of 2-substituted quinoxalines by Ga(ClO 4) 3-catalyzed cycloaddition of α- hydroxyketones and o-phenylenediamines is introduced. The reaction is catalyzed by 10 mol \% of Ga(ClO 4) 3 in EtOH at room temperature. It is performed under simple and mild conditions to afford the product in good yield.",

keywords = "α-Hydroxyketones, Cycloaddition, Gallium perchlorate, o-Phenylenediamines, Quinoxalines",

author = "Fan Pan and Chen, \{Tang Ming\} and Cao, \{Jia Jia\} and Zou, \{Jian Ping\} and Wei Zhang",

year = "2012",

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doi = "10.1016/j.tetlet.2012.02.113",

language = "English",

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journal = "Tetrahedron Letters",

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T1 - Ga(ClO 4) 3-catalyzed synthesis of quinoxalines by cycloaddition of α-hydroxyketones and o-phenylenediamines

AU - Pan, Fan

AU - Chen, Tang Ming

AU - Cao, Jia Jia

AU - Zou, Jian Ping

AU - Zhang, Wei

PY - 2012/5/16

Y1 - 2012/5/16

N2 - A new approach for the synthesis of 2-substituted quinoxalines by Ga(ClO 4) 3-catalyzed cycloaddition of α- hydroxyketones and o-phenylenediamines is introduced. The reaction is catalyzed by 10 mol % of Ga(ClO 4) 3 in EtOH at room temperature. It is performed under simple and mild conditions to afford the product in good yield.

AB - A new approach for the synthesis of 2-substituted quinoxalines by Ga(ClO 4) 3-catalyzed cycloaddition of α- hydroxyketones and o-phenylenediamines is introduced. The reaction is catalyzed by 10 mol % of Ga(ClO 4) 3 in EtOH at room temperature. It is performed under simple and mild conditions to afford the product in good yield.

KW - α-Hydroxyketones

KW - Cycloaddition

KW - Gallium perchlorate

KW - o-Phenylenediamines

KW - Quinoxalines

UR - https://www.scopus.com/pages/publications/84859760879

UR - https://www.scopus.com/pages/publications/84859760879#tab=citedBy

U2 - 10.1016/j.tetlet.2012.02.113

DO - 10.1016/j.tetlet.2012.02.113

M3 - Article

AN - SCOPUS:84859760879

SN - 0040-4039

VL - 53

SP - 2508

EP - 2510

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 20

ER -