Human applications of transcranial temporal interference stimulation: A systematic review

Ilya Demchenko; Ishaan Tailor; Sina Chegini; Haochen Yu; Fatemeh Gholamali Nezhad; Alice Rueda; Anne Kever; Sridhar Krishnan; Abhishek Datta; Jed A. Meltzer; Simon J. Graham; Tom A. Schweizer; Sumientra Rampersad; Edward S. Boyden; Ines R. Violante; Robert Chen; Andres M. Lozano; Venkat Bhat

doi:10.1016/j.brs.2025.10.023

Human applications of transcranial temporal interference stimulation: A systematic review

Ilya Demchenko
, Ishaan Tailor
, Sina Chegini
, Haochen Yu
, Fatemeh Gholamali Nezhad
, Alice Rueda
, Anne Kever
, Sridhar Krishnan
, Abhishek Datta
, Jed A. Meltzer
, Simon J. Graham
, Tom A. Schweizer
, Sumientra Rampersad
, Edward S. Boyden
, Ines R. Violante
, Robert Chen
, Andres M. Lozano
, Venkat Bhat

Physics

Research output: Contribution to journal › Review article › peer-review

Original language	English
Pages (from-to)	2054-2066
Number of pages	13
Journal	Brain Stimulation
Volume	18
Issue number	6
DOIs	https://doi.org/10.1016/j.brs.2025.10.023
State	Published - Nov 1 2025

ASJC Scopus Subject Areas

General Neuroscience
Biophysics
Clinical Neurology

Keywords

Brain
Clinical study
Deep brain stimulation
Electric stimulation
Humans
Systematic review
Temporal interference

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10.1016/j.brs.2025.10.023

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Demchenko, I., Tailor, I., Chegini, S., Yu, H., Gholamali Nezhad, F., Rueda, A., Kever, A., Krishnan, S., Datta, A., Meltzer, J. A., Graham, S. J., Schweizer, T. A., Rampersad, S., Boyden, E. S., Violante, I. R., Chen, R., Lozano, A. M., & Bhat, V. (2025). Human applications of transcranial temporal interference stimulation: A systematic review. Brain Stimulation, 18(6), 2054-2066. https://doi.org/10.1016/j.brs.2025.10.023

Demchenko, I, Tailor, I, Chegini, S, Yu, H, Gholamali Nezhad, F, Rueda, A, Kever, A, Krishnan, S, Datta, A, Meltzer, JA, Graham, SJ, Schweizer, TA, Rampersad, S, Boyden, ES, Violante, IR, Chen, R, Lozano, AM & Bhat, V 2025, 'Human applications of transcranial temporal interference stimulation: A systematic review', Brain Stimulation, vol. 18, no. 6, pp. 2054-2066. https://doi.org/10.1016/j.brs.2025.10.023

@article{2b4f6a858d4f45208bc97ff1768496ef,

title = "Human applications of transcranial temporal interference stimulation: A systematic review",

keywords = "Brain, Clinical study, Deep brain stimulation, Electric stimulation, Humans, Systematic review, Temporal interference",

author = "Ilya Demchenko and Ishaan Tailor and Sina Chegini and Haochen Yu and \{Gholamali Nezhad\}, Fatemeh and Alice Rueda and Anne Kever and Sridhar Krishnan and Abhishek Datta and Meltzer, \{Jed A.\} and Graham, \{Simon J.\} and Schweizer, \{Tom A.\} and Sumientra Rampersad and Boyden, \{Edward S.\} and Violante, \{Ines R.\} and Robert Chen and Lozano, \{Andres M.\} and Venkat Bhat",

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year = "2025",

month = nov,

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doi = "10.1016/j.brs.2025.10.023",

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T1 - Human applications of transcranial temporal interference stimulation

T2 - A systematic review

AU - Demchenko, Ilya

AU - Tailor, Ishaan

AU - Chegini, Sina

AU - Yu, Haochen

AU - Gholamali Nezhad, Fatemeh

AU - Rueda, Alice

AU - Kever, Anne

AU - Krishnan, Sridhar

AU - Datta, Abhishek

AU - Meltzer, Jed A.

AU - Graham, Simon J.

AU - Schweizer, Tom A.

AU - Rampersad, Sumientra

AU - Boyden, Edward S.

AU - Violante, Ines R.

AU - Chen, Robert

AU - Lozano, Andres M.

AU - Bhat, Venkat

PY - 2025/11/1

Y1 - 2025/11/1

KW - Brain

KW - Clinical study

KW - Deep brain stimulation

KW - Electric stimulation

KW - Humans

KW - Systematic review

KW - Temporal interference

UR - https://www.scopus.com/pages/publications/105020807846

UR - https://www.scopus.com/pages/publications/105020807846#tab=citedBy

U2 - 10.1016/j.brs.2025.10.023

DO - 10.1016/j.brs.2025.10.023

M3 - Review article

C2 - 40835066

AN - SCOPUS:105020807846

SN - 1935-861X

VL - 18

SP - 2054

EP - 2066

JO - Brain Stimulation

JF - Brain Stimulation

IS - 6

ER -

Human applications of transcranial temporal interference stimulation: A systematic review

ASJC Scopus Subject Areas

Keywords

Access to Document

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