Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress

  • Yiji Liao
  • , Chen Hao Chen
  • , Tengfei Xiao
  • , Bárbara de la Peña Avalos
  • , Eloise V. Dray
  • , Changmeng Cai
  • , Shuai Gao
  • , Neel Shah
  • , Zhao Zhang
  • , Avery Feit
  • , Pengya Xue
  • , Zhijie Liu
  • , Mei Yang
  • , Ji Hoon Lee
  • , Han Xu
  • , Wei Li
  • , Shenglin Mei
  • , Roodolph S. Pierre
  • , Shaokun Shu
  • , Teng Fei
  • Melissa Duarte, Jin Zhao, James E. Bradner, Kornelia Polyak, Philip W. Kantoff, Henry Long, Steven P. Balk, X. Shirley Liu, Myles Brown, Kexin Xu

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article numbere2105898119
JournalProceedings of the National Academy of Sciences of the United States of America
Volume119
Issue number3
DOIs
StatePublished - Jan 18 2022

ASJC Scopus Subject Areas

  • General

Keywords

  • Cancer therapy
  • DNA damage repair
  • EZH2 inhibitors
  • Mechanism of drug action

Fingerprint

Dive into the research topics of 'Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress'. Together they form a unique fingerprint.

Cite this