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K-10-catalyzed highly diastereoselective synthesis of aziridines

  • University of Massachusetts Boston

Research output: Contribution to journal › Article › peer-review

Abstract

A new solid acid-catalyzed method was developed for the stereoselective preparation of cis-aziridines from imines and ethyl diazoacetate using montmorillonite K-10 as catalyst. The reactions proceeded readily at room temperature in short reaction times, providing the products in excellent yields (90%) and exclusive selectivity.

Original languageEnglish
Pages (from-to)745-748
Number of pages4
JournalSynlett
Issue number5
DOIs
StatePublished - 2010

ASJC Scopus Subject Areas

  • Organic Chemistry

Keywords

  • Aziridines
  • Ethyl diazo-acetate
  • Heterogeneous catalysis
  • Imines
  • Montmorillonite K-10

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