Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis

Min Qiu; Yan Tang; Jinjin Chen; Rachel Muriph; Zhongfeng Ye; Changfeng Huang; Jason Evans; Elizabeth P. Henske; Qiaobing Xu

doi:10.1073/pnas.2116271119

Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis

Min Qiu
, Yan Tang
, Jinjin Chen
, Rachel Muriph
, Zhongfeng Ye
, Changfeng Huang
, Jason Evans
, Elizabeth P. Henske
, Qiaobing Xu

Chemistry

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	e2116271119
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	119
Issue number	8
DOIs	https://doi.org/10.1073/pnas.2116271119
State	Published - Feb 22 2022

ASJC Scopus Subject Areas

General

Keywords

Lipid nanoparticles
Lung-targeted delivery
Lymphangioleiomyomatosis
mRNA
Tuberous sclerosis complex

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10.1073/pnas.2116271119

Cite this

Qiu, M., Tang, Y., Chen, J., Muriph, R., Ye, Z., Huang, C., Evans, J., Henske, E. P., & Xu, Q. (2022). Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis. Proceedings of the National Academy of Sciences of the United States of America, 119(8), Article e2116271119. https://doi.org/10.1073/pnas.2116271119

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author = "Min Qiu and Yan Tang and Jinjin Chen and Rachel Muriph and Zhongfeng Ye and Changfeng Huang and Jason Evans and Henske, \{Elizabeth P.\} and Qiaobing Xu",

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T1 - Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis

AU - Qiu, Min

AU - Tang, Yan

AU - Chen, Jinjin

AU - Muriph, Rachel

AU - Ye, Zhongfeng

AU - Huang, Changfeng

AU - Evans, Jason

AU - Henske, Elizabeth P.

AU - Xu, Qiaobing

PY - 2022/2/22

Y1 - 2022/2/22

KW - Lipid nanoparticles

KW - Lung-targeted delivery

KW - Lymphangioleiomyomatosis

KW - mRNA

KW - Tuberous sclerosis complex

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U2 - 10.1073/pnas.2116271119

DO - 10.1073/pnas.2116271119

M3 - Article

C2 - 35173043

AN - SCOPUS:85124776692

SN - 0027-8424

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JO - Proceedings of the National Academy of Sciences of the United States of America

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Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis

ASJC Scopus Subject Areas

Keywords

Access to Document

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