Multiomics analysis unveils an inosine-sensitive DNA damage response in neurogenic bladder after spinal cord injury

Ali Hashemi Gheinani; Bryan S. Sack; Alexander Bigger-Allen; Hatim Thaker; Hussein Atta; George Lambrinos; Kyle Costa; Claire Doyle; Mehrnaz Gharaee-Kermani; Susan Patalano; Mary Piper; Justin F. Cotellessa; Dijana Vitko; Haiying Li; Manubhai Kadayil Prabhakaran; Vivian Cristofaro; John Froehlich; Richard S. Lee; Wei Yang; Maryrose P. Sullivan; Jill A. Macoska; Rosalyn M. Adam

doi:10.1172/jci.insight.180275

Multiomics analysis unveils an inosine-sensitive DNA damage response in neurogenic bladder after spinal cord injury

Ali Hashemi Gheinani
, Bryan S. Sack
, Alexander Bigger-Allen
, Hatim Thaker
, Hussein Atta
, George Lambrinos
, Kyle Costa
, Claire Doyle
, Mehrnaz Gharaee-Kermani
, Susan Patalano
, Mary Piper
, Justin F. Cotellessa
, Dijana Vitko
, Haiying Li
, Manubhai Kadayil Prabhakaran
, Vivian Cristofaro
, John Froehlich
, Richard S. Lee
, Wei Yang
, Maryrose P. Sullivan

Jill A. Macoska, Rosalyn M. Adam

Biology

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	e180275
Journal	JCI Insight
Volume	10
Issue number	12
DOIs	https://doi.org/10.1172/jci.insight.180275
State	Published - Jun 2025

ASJC Scopus Subject Areas

General Medicine

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10.1172/jci.insight.180275

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Gheinani, A. H., Sack, B. S., Bigger-Allen, A., Thaker, H., Atta, H., Lambrinos, G., Costa, K., Doyle, C., Gharaee-Kermani, M., Patalano, S., Piper, M., Cotellessa, J. F., Vitko, D., Li, H., Prabhakaran, M. K., Cristofaro, V., Froehlich, J., Lee, R. S., Yang, W., ... Adam, R. M. (2025). Multiomics analysis unveils an inosine-sensitive DNA damage response in neurogenic bladder after spinal cord injury. JCI Insight, 10(12), Article e180275. https://doi.org/10.1172/jci.insight.180275

Gheinani, AH, Sack, BS, Bigger-Allen, A, Thaker, H, Atta, H, Lambrinos, G, Costa, K, Doyle, C, Gharaee-Kermani, M, Patalano, S, Piper, M, Cotellessa, JF, Vitko, D, Li, H, Prabhakaran, MK, Cristofaro, V, Froehlich, J, Lee, RS, Yang, W, Sullivan, MP, Macoska, JA & Adam, RM 2025, 'Multiomics analysis unveils an inosine-sensitive DNA damage response in neurogenic bladder after spinal cord injury', JCI Insight, vol. 10, no. 12, e180275. https://doi.org/10.1172/jci.insight.180275

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author = "Gheinani, \{Ali Hashemi\} and Sack, \{Bryan S.\} and Alexander Bigger-Allen and Hatim Thaker and Hussein Atta and George Lambrinos and Kyle Costa and Claire Doyle and Mehrnaz Gharaee-Kermani and Susan Patalano and Mary Piper and Cotellessa, \{Justin F.\} and Dijana Vitko and Haiying Li and Prabhakaran, \{Manubhai Kadayil\} and Vivian Cristofaro and John Froehlich and Lee, \{Richard S.\} and Wei Yang and Sullivan, \{Maryrose P.\} and Macoska, \{Jill A.\} and Adam, \{Rosalyn M.\}",

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year = "2025",

month = jun,

doi = "10.1172/jci.insight.180275",

language = "English",

volume = "10",

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AU - Gheinani, Ali Hashemi

AU - Sack, Bryan S.

AU - Bigger-Allen, Alexander

AU - Thaker, Hatim

AU - Atta, Hussein

AU - Lambrinos, George

AU - Costa, Kyle

AU - Doyle, Claire

AU - Gharaee-Kermani, Mehrnaz

AU - Patalano, Susan

AU - Piper, Mary

AU - Cotellessa, Justin F.

AU - Vitko, Dijana

AU - Li, Haiying

AU - Prabhakaran, Manubhai Kadayil

AU - Cristofaro, Vivian

AU - Froehlich, John

AU - Lee, Richard S.

AU - Yang, Wei

AU - Sullivan, Maryrose P.

AU - Macoska, Jill A.

AU - Adam, Rosalyn M.

PY - 2025/6

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UR - https://www.scopus.com/pages/publications/105009440297#tab=citedBy

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AN - SCOPUS:105009440297

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JO - JCI Insight

JF - JCI Insight

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ER -

Multiomics analysis unveils an inosine-sensitive DNA damage response in neurogenic bladder after spinal cord injury

ASJC Scopus Subject Areas

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