Abstract
A new method for the synthesis of heterocyclic systems containing tetrazole and tetrahydroisoquinoline is developed via the performance of one-pot Ugi-azide and Heck cyclization reactions. The integration of the multicomponent and post-condensation reactions in one-pot maximizes the pot-, atom-, and step-economy (PASE).
| Original language | English |
|---|---|
| Pages (from-to) | 912-920 |
| Number of pages | 9 |
| Journal | Beilstein Journal of Organic Chemistry |
| Volume | 20 |
| DOIs | |
| State | Published - 2024 |
ASJC Scopus Subject Areas
- Organic Chemistry
Keywords
- Heck reaction
- one-pot
- tetrahydroisoquinoline
- tetrazole
- tetrazolo-pyrazino[2,1-a]isoquinolin-6(5H)-ones
- Ugi-azide reaction
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