TY - GEN
T1 - Photodynamic Therapy of Oral Cavity Tumors in Low Resource Settings
T2 - 2019 IEEE Photonics Conference, IPC 2019
AU - Mallidi, Srivalleesha
AU - Siddique, Shahid A.
AU - Akhtar, Kafil
AU - August, Meredith
AU - Troulis, Maria
AU - Cuckov, Filip
AU - Celli, Jonathan
AU - Hasan, Tayyaba
AU - Khan, Amjad
AU - Liu, Hui
AU - Daly, Liam
AU - Rudd, Grant
AU - Leon, Paola
AU - Khan, Shakir
AU - Hussain, Bilal
AU - Hasan, Syed A.
N1 - Publisher Copyright:
© 2019 IEEE.
PY - 2019/9
Y1 - 2019/9
N2 - Oral cancer is one of the leading diseases in the Southeast Asian countries due to unhealthy habits (chewing of tobacco and related preparations like Gutka). Surgery, radiotherapy and chemotherapy are expensive, require significant infrastructure and have detrimental side effects and lead to poor quality of life. We present a light-based therapy namely Photodynamic therapy (PDT) that showed promise, specifically excellent mucosal healing, in treatment of oral cancers and other malignancies. To make PDT a low-cost modality, we custom designed a battery powered light source coupled with fiber delivery and oral applicators for irradiating the lesion field. Here we demonstrate the stability of the oral applicators in human mouth followed by a pilot study in oral cancer patients to demonstrate therapy response with our custom-built light delivery system.
AB - Oral cancer is one of the leading diseases in the Southeast Asian countries due to unhealthy habits (chewing of tobacco and related preparations like Gutka). Surgery, radiotherapy and chemotherapy are expensive, require significant infrastructure and have detrimental side effects and lead to poor quality of life. We present a light-based therapy namely Photodynamic therapy (PDT) that showed promise, specifically excellent mucosal healing, in treatment of oral cancers and other malignancies. To make PDT a low-cost modality, we custom designed a battery powered light source coupled with fiber delivery and oral applicators for irradiating the lesion field. Here we demonstrate the stability of the oral applicators in human mouth followed by a pilot study in oral cancer patients to demonstrate therapy response with our custom-built light delivery system.
KW - low resource settings
KW - oral cancer
KW - photodynamic therapy
UR - https://www.scopus.com/pages/publications/85075903191
UR - https://www.scopus.com/pages/publications/85075903191#tab=citedBy
U2 - 10.1109/IPCon.2019.8908373
DO - 10.1109/IPCon.2019.8908373
M3 - Conference contribution
AN - SCOPUS:85075903191
T3 - 2019 IEEE Photonics Conference, IPC 2019 - Proceedings
BT - 2019 IEEE Photonics Conference, IPC 2019 - Proceedings
PB - Institute of Electrical and Electronics Engineers Inc.
Y2 - 29 September 2019 through 3 October 2019
ER -