PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

Prasidda Khadka; Zachary J. Reitman; Sophie Lu; Graham Buchan; Gabrielle Gionet; Frank Dubois; Diana M. Carvalho; Juliann Shih; Shu Zhang; Noah F. Greenwald; Travis Zack; Ofer Shapira; Kristine Pelton; Rachel Hartley; Heather Bear; Yohanna Georgis; Spandana Jarmale; Randy Melanson; Kevin Bonanno; Kathleen Schoolcraft; Peter G. Miller; Alexandra L. Condurat; Elizabeth M. Gonzalez; Kenin Qian; Eric Morin; Jaldeep Langhnoja; Leslie E. Lupien; Veronica Rendo; Jeromy Digiacomo; Dayle Wang; Kevin Zhou; Rushil Kumbhani; Maria E. Guerra Garcia; Claire E. Sinai; Sarah Becker; Rachel Schneider; Jayne Vogelzang; Karsten Krug; Amy Goodale; Tanaz Abid; Zohra Kalani; Federica Piccioni; Rameen Beroukhim; Nicole S. Persky; David E. Root; Angel M. Carcaboso; Benjamin L. Ebert; Christine Fuller; Ozgun Babur; Mark W. Kieran; Chris Jones; Hasmik Keshishian; Keith L. Ligon; Steven A. Carr; Timothy N. Phoenix; Pratiti Bandopadhayay

doi:10.1038/s41467-022-28198-8

PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

Prasidda Khadka
, Zachary J. Reitman
, Sophie Lu
, Graham Buchan
, Gabrielle Gionet
, Frank Dubois
, Diana M. Carvalho
, Juliann Shih
, Shu Zhang
, Noah F. Greenwald
, Travis Zack
, Ofer Shapira
, Kristine Pelton
, Rachel Hartley
, Heather Bear
, Yohanna Georgis
, Spandana Jarmale
, Randy Melanson
, Kevin Bonanno
, Kathleen Schoolcraft

Peter G. Miller, Alexandra L. Condurat, Elizabeth M. Gonzalez, Kenin Qian, Eric Morin, Jaldeep Langhnoja, Leslie E. Lupien, Veronica Rendo, Jeromy Digiacomo, Dayle Wang, Kevin Zhou, Rushil Kumbhani, Maria E. Guerra Garcia, Claire E. Sinai, Sarah Becker, Rachel Schneider, Jayne Vogelzang, Karsten Krug, Amy Goodale, Tanaz Abid, Zohra Kalani, Federica Piccioni, Rameen Beroukhim, Nicole S. Persky, David E. Root, Angel M. Carcaboso, Benjamin L. Ebert, Christine Fuller, Ozgun Babur, Mark W. Kieran, Chris Jones, Hasmik Keshishian, Keith L. Ligon, Steven A. Carr, Timothy N. Phoenix, Pratiti Bandopadhayay

Computer Science

Research output: Contribution to journal › Article › peer-review

Original language	English
Article number	604
Journal	Nature Communications
Volume	13
Issue number	1
DOIs	https://doi.org/10.1038/s41467-022-28198-8
State	Published - Dec 2022

ASJC Scopus Subject Areas

General Chemistry
General Biochemistry,Genetics and Molecular Biology
General Physics and Astronomy

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10.1038/s41467-022-28198-8

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Khadka, P., Reitman, Z. J., Lu, S., Buchan, G., Gionet, G., Dubois, F., Carvalho, D. M., Shih, J., Zhang, S., Greenwald, N. F., Zack, T., Shapira, O., Pelton, K., Hartley, R., Bear, H., Georgis, Y., Jarmale, S., Melanson, R., Bonanno, K., ... Bandopadhayay, P. (2022). PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation. Nature Communications, 13(1), Article 604. https://doi.org/10.1038/s41467-022-28198-8

Khadka, P, Reitman, ZJ, Lu, S, Buchan, G, Gionet, G, Dubois, F, Carvalho, DM, Shih, J, Zhang, S, Greenwald, NF, Zack, T, Shapira, O, Pelton, K, Hartley, R, Bear, H, Georgis, Y, Jarmale, S, Melanson, R, Bonanno, K, Schoolcraft, K, Miller, PG, Condurat, AL, Gonzalez, EM, Qian, K, Morin, E, Langhnoja, J, Lupien, LE, Rendo, V, Digiacomo, J, Wang, D, Zhou, K, Kumbhani, R, Guerra Garcia, ME, Sinai, CE, Becker, S, Schneider, R, Vogelzang, J, Krug, K, Goodale, A, Abid, T, Kalani, Z, Piccioni, F, Beroukhim, R, Persky, NS, Root, DE, Carcaboso, AM, Ebert, BL, Fuller, C, Babur, O, Kieran, MW, Jones, C, Keshishian, H, Ligon, KL, Carr, SA, Phoenix, TN & Bandopadhayay, P 2022, 'PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation', Nature Communications, vol. 13, no. 1, 604. https://doi.org/10.1038/s41467-022-28198-8

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title = "PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation",

author = "Prasidda Khadka and Reitman, \{Zachary J.\} and Sophie Lu and Graham Buchan and Gabrielle Gionet and Frank Dubois and Carvalho, \{Diana M.\} and Juliann Shih and Shu Zhang and Greenwald, \{Noah F.\} and Travis Zack and Ofer Shapira and Kristine Pelton and Rachel Hartley and Heather Bear and Yohanna Georgis and Spandana Jarmale and Randy Melanson and Kevin Bonanno and Kathleen Schoolcraft and Miller, \{Peter G.\} and Condurat, \{Alexandra L.\} and Gonzalez, \{Elizabeth M.\} and Kenin Qian and Eric Morin and Jaldeep Langhnoja and Lupien, \{Leslie E.\} and Veronica Rendo and Jeromy Digiacomo and Dayle Wang and Kevin Zhou and Rushil Kumbhani and \{Guerra Garcia\}, \{Maria E.\} and Sinai, \{Claire E.\} and Sarah Becker and Rachel Schneider and Jayne Vogelzang and Karsten Krug and Amy Goodale and Tanaz Abid and Zohra Kalani and Federica Piccioni and Rameen Beroukhim and Persky, \{Nicole S.\} and Root, \{David E.\} and Carcaboso, \{Angel M.\} and Ebert, \{Benjamin L.\} and Christine Fuller and Ozgun Babur and Kieran, \{Mark W.\} and Chris Jones and Hasmik Keshishian and Ligon, \{Keith L.\} and Carr, \{Steven A.\} and Phoenix, \{Timothy N.\} and Pratiti Bandopadhayay",

note = "Publisher Copyright: {\textcopyright} 2022, The Author(s).",

year = "2022",

month = dec,

doi = "10.1038/s41467-022-28198-8",

language = "English",

volume = "13",

journal = "Nature Communications",

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T1 - PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

AU - Khadka, Prasidda

AU - Reitman, Zachary J.

AU - Lu, Sophie

AU - Buchan, Graham

AU - Gionet, Gabrielle

AU - Dubois, Frank

AU - Carvalho, Diana M.

AU - Shih, Juliann

AU - Zhang, Shu

AU - Greenwald, Noah F.

AU - Zack, Travis

AU - Shapira, Ofer

AU - Pelton, Kristine

AU - Hartley, Rachel

AU - Bear, Heather

AU - Georgis, Yohanna

AU - Jarmale, Spandana

AU - Melanson, Randy

AU - Bonanno, Kevin

AU - Schoolcraft, Kathleen

AU - Miller, Peter G.

AU - Condurat, Alexandra L.

AU - Gonzalez, Elizabeth M.

AU - Qian, Kenin

AU - Morin, Eric

AU - Langhnoja, Jaldeep

AU - Lupien, Leslie E.

AU - Rendo, Veronica

AU - Digiacomo, Jeromy

AU - Wang, Dayle

AU - Zhou, Kevin

AU - Kumbhani, Rushil

AU - Guerra Garcia, Maria E.

AU - Sinai, Claire E.

AU - Becker, Sarah

AU - Schneider, Rachel

AU - Vogelzang, Jayne

AU - Krug, Karsten

AU - Goodale, Amy

AU - Abid, Tanaz

AU - Kalani, Zohra

AU - Piccioni, Federica

AU - Beroukhim, Rameen

AU - Persky, Nicole S.

AU - Root, David E.

AU - Carcaboso, Angel M.

AU - Ebert, Benjamin L.

AU - Fuller, Christine

AU - Babur, Ozgun

AU - Kieran, Mark W.

AU - Jones, Chris

AU - Keshishian, Hasmik

AU - Ligon, Keith L.

AU - Carr, Steven A.

AU - Phoenix, Timothy N.

AU - Bandopadhayay, Pratiti

PY - 2022/12

Y1 - 2022/12

UR - https://www.scopus.com/pages/publications/85123972540

UR - https://www.scopus.com/pages/publications/85123972540#tab=citedBy

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DO - 10.1038/s41467-022-28198-8

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C2 - 35105861

AN - SCOPUS:85123972540

SN - 2041-1723

VL - 13

JO - Nature Communications

JF - Nature Communications

IS - 1

M1 - 604

ER -

PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

ASJC Scopus Subject Areas

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