Recyclable gallium(III) triflate-catalyzed [4+3] cycloaddition for synthesis of 2,4-disubstituted-3H-benzo[b][1,4]diazepines

Shi Gang Huang; Hai Feng Mao; Shao Fang Zhou; Jian Ping Zou; Wei Zhang

doi:10.1016/j.tetlet.2013.08.092

Recyclable gallium(III) triflate-catalyzed [4+3] cycloaddition for synthesis of 2,4-disubstituted-3H-benzo[b][1,4]diazepines

Shi Gang Huang
, Hai Feng Mao
, Shao Fang Zhou
, Jian Ping Zou
, Wei Zhang

Chemistry

Soochow University
CAS - Shanghai Institute of Organic Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Simple and efficient Ga(OTf)₃-catalyzed [4+3] cycloaddition of 1,3-diarylpropynones and o-phenylenediamines is developed for the preparation of 2,4-disubstituted-3H-benzo[b][1,4]diazepines. The reaction has advantages of using a green solvent, generating a minimal amount of waste, and easy catalyst recycle.

Original language	English
Pages (from-to)	6178-6180
Number of pages	3
Journal	Tetrahedron Letters
Volume	54
Issue number	46
DOIs	https://doi.org/10.1016/j.tetlet.2013.08.092
State	Published - Nov 13 2013

ASJC Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

Keywords

1,3-Diarylpropynones
2,4-Disubstituted-3H-benzo[b][1,4]diazepines
Catalysis [4+3]
Cycloaddition
Ga(OTf)

Access to Document

10.1016/j.tetlet.2013.08.092

Cite this

@article{f3f2192818bf48d0ae3f1157be57efe7,

title = "Recyclable gallium(III) triflate-catalyzed [4+3] cycloaddition for synthesis of 2,4-disubstituted-3H-benzo[b][1,4]diazepines",

abstract = "Simple and efficient Ga(OTf)3-catalyzed [4+3] cycloaddition of 1,3-diarylpropynones and o-phenylenediamines is developed for the preparation of 2,4-disubstituted-3H-benzo[b][1,4]diazepines. The reaction has advantages of using a green solvent, generating a minimal amount of waste, and easy catalyst recycle.",

keywords = "1,3-Diarylpropynones, 2,4-Disubstituted-3H-benzo[b][1,4]diazepines, Catalysis [4+3], Cycloaddition, Ga(OTf)",

author = "Huang, \{Shi Gang\} and Mao, \{Hai Feng\} and Zhou, \{Shao Fang\} and Zou, \{Jian Ping\} and Wei Zhang",

year = "2013",

month = nov,

day = "13",

doi = "10.1016/j.tetlet.2013.08.092",

language = "English",

volume = "54",

pages = "6178--6180",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "46",

}

TY - JOUR

T1 - Recyclable gallium(III) triflate-catalyzed [4+3] cycloaddition for synthesis of 2,4-disubstituted-3H-benzo[b][1,4]diazepines

AU - Huang, Shi Gang

AU - Mao, Hai Feng

AU - Zhou, Shao Fang

AU - Zou, Jian Ping

AU - Zhang, Wei

PY - 2013/11/13

Y1 - 2013/11/13

N2 - Simple and efficient Ga(OTf)3-catalyzed [4+3] cycloaddition of 1,3-diarylpropynones and o-phenylenediamines is developed for the preparation of 2,4-disubstituted-3H-benzo[b][1,4]diazepines. The reaction has advantages of using a green solvent, generating a minimal amount of waste, and easy catalyst recycle.

AB - Simple and efficient Ga(OTf)3-catalyzed [4+3] cycloaddition of 1,3-diarylpropynones and o-phenylenediamines is developed for the preparation of 2,4-disubstituted-3H-benzo[b][1,4]diazepines. The reaction has advantages of using a green solvent, generating a minimal amount of waste, and easy catalyst recycle.

KW - 1,3-Diarylpropynones

KW - 2,4-Disubstituted-3H-benzo[b][1,4]diazepines

KW - Catalysis [4+3]

KW - Cycloaddition

KW - Ga(OTf)

UR - https://www.scopus.com/pages/publications/84885483597

UR - https://www.scopus.com/pages/publications/84885483597#tab=citedBy

U2 - 10.1016/j.tetlet.2013.08.092

DO - 10.1016/j.tetlet.2013.08.092

M3 - Article

AN - SCOPUS:84885483597

SN - 0040-4039

VL - 54

SP - 6178

EP - 6180

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 46

ER -

Recyclable gallium(III) triflate-catalyzed [4+3] cycloaddition for synthesis of 2,4-disubstituted-3H-benzo[b][1,4]diazepines

Abstract

ASJC Scopus Subject Areas

Keywords

Access to Document

Other files and links

Fingerprint

Cite this