Replication stress and defective checkpoints make fallopian tube epithelial cells putative drivers of high-grade serous ovarian cancer

  • Pamoda Galhenage
  • , Yunlan Zhou
  • , Erica Perry
  • , Brenda Loc
  • , Kelly Fietz
  • , Sonia Iyer
  • , Ferenc Reinhardt
  • , Tiego Da Silva
  • , Vladimir Botchkarev
  • , Jie Chen
  • , Christopher P. Crum
  • , Robert A. Weinberg
  • , Shailja Pathania

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Article number113144
JournalCell Reports
Volume42
Issue number10
DOIs
StatePublished - Oct 31 2023

ASJC Scopus Subject Areas

  • General Biochemistry,Genetics and Molecular Biology

Keywords

  • BRCA1
  • Cell of origin
  • CP: Cancer
  • DNA damage checkpoints
  • DNA damage repair
  • fallopian tube
  • fimbrial ends
  • High-grade serous ovarian cancer
  • ovarian fat pad injection
  • replication stress
  • replication stress marker

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