Small-Molecule Dual PLK1 and BRD4 Inhibitors are Active Against Preclinical Models of Pediatric Solid Tumors

Natalie Timme; Youjia Han; Shuai Liu; Hailemichael O. Yosief; Heathcliff Dorado García; Yi Bei; Filippos Klironomos; Ian C. MacArthur; Annabell Szymansky; Jennifer von Stebut; Victor Bardinet; Constantin Dohna; Annette Künkele; Jana Rolff; Patrick Hundsdörfer; Andrej Lissat; Georg Seifert; Angelika Eggert; Johannes H. Schulte; Wei Zhang; Anton G. Henssen

doi:10.1016/j.tranon.2019.09.013

Small-Molecule Dual PLK1 and BRD4 Inhibitors are Active Against Preclinical Models of Pediatric Solid Tumors

Natalie Timme
, Youjia Han
, Shuai Liu
, Hailemichael O. Yosief
, Heathcliff Dorado García
, Yi Bei
, Filippos Klironomos
, Ian C. MacArthur
, Annabell Szymansky
, Jennifer von Stebut
, Victor Bardinet
, Constantin Dohna
, Annette Künkele
, Jana Rolff
, Patrick Hundsdörfer
, Andrej Lissat
, Georg Seifert
, Angelika Eggert
, Johannes H. Schulte
, Wei Zhang

Anton G. Henssen

Chemistry

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	221-232
Number of pages	12
Journal	Translational Oncology
Volume	13
Issue number	2
DOIs	https://doi.org/10.1016/j.tranon.2019.09.013
State	Published - Feb 2020

ASJC Scopus Subject Areas

Oncology
Cancer Research

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10.1016/j.tranon.2019.09.013

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Timme, N., Han, Y., Liu, S., Yosief, H. O., García, H. D., Bei, Y., Klironomos, F., MacArthur, I. C., Szymansky, A., von Stebut, J., Bardinet, V., Dohna, C., Künkele, A., Rolff, J., Hundsdörfer, P., Lissat, A., Seifert, G., Eggert, A., Schulte, J. H., ... Henssen, A. G. (2020). Small-Molecule Dual PLK1 and BRD4 Inhibitors are Active Against Preclinical Models of Pediatric Solid Tumors. Translational Oncology, 13(2), 221-232. https://doi.org/10.1016/j.tranon.2019.09.013

Timme, N, Han, Y, Liu, S, Yosief, HO, García, HD, Bei, Y, Klironomos, F, MacArthur, IC, Szymansky, A, von Stebut, J, Bardinet, V, Dohna, C, Künkele, A, Rolff, J, Hundsdörfer, P, Lissat, A, Seifert, G, Eggert, A, Schulte, JH, Zhang, W & Henssen, AG 2020, 'Small-Molecule Dual PLK1 and BRD4 Inhibitors are Active Against Preclinical Models of Pediatric Solid Tumors', Translational Oncology, vol. 13, no. 2, pp. 221-232. https://doi.org/10.1016/j.tranon.2019.09.013

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title = "Small-Molecule Dual PLK1 and BRD4 Inhibitors are Active Against Preclinical Models of Pediatric Solid Tumors",

author = "Natalie Timme and Youjia Han and Shuai Liu and Yosief, \{Hailemichael O.\} and Garc{\'i}a, \{Heathcliff Dorado\} and Yi Bei and Filippos Klironomos and MacArthur, \{Ian C.\} and Annabell Szymansky and \{von Stebut\}, Jennifer and Victor Bardinet and Constantin Dohna and Annette K{\"u}nkele and Jana Rolff and Patrick Hundsd{\"o}rfer and Andrej Lissat and Georg Seifert and Angelika Eggert and Schulte, \{Johannes H.\} and Wei Zhang and Henssen, \{Anton G.\}",

note = "Publisher Copyright: {\textcopyright} 2019 The Authors",

year = "2020",

month = feb,

doi = "10.1016/j.tranon.2019.09.013",

language = "English",

volume = "13",

pages = "221--232",

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AU - Timme, Natalie

AU - Han, Youjia

AU - Liu, Shuai

AU - Yosief, Hailemichael O.

AU - García, Heathcliff Dorado

AU - Bei, Yi

AU - Klironomos, Filippos

AU - MacArthur, Ian C.

AU - Szymansky, Annabell

AU - von Stebut, Jennifer

AU - Bardinet, Victor

AU - Dohna, Constantin

AU - Künkele, Annette

AU - Rolff, Jana

AU - Hundsdörfer, Patrick

AU - Lissat, Andrej

AU - Seifert, Georg

AU - Eggert, Angelika

AU - Schulte, Johannes H.

AU - Zhang, Wei

AU - Henssen, Anton G.

PY - 2020/2

Y1 - 2020/2

UR - https://www.scopus.com/pages/publications/85076707676

UR - https://www.scopus.com/pages/publications/85076707676#tab=citedBy

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DO - 10.1016/j.tranon.2019.09.013

M3 - Article

AN - SCOPUS:85076707676

SN - 1936-5233

VL - 13

SP - 221

EP - 232

JO - Translational Oncology

JF - Translational Oncology

IS - 2

ER -

Small-Molecule Dual PLK1 and BRD4 Inhibitors are Active Against Preclinical Models of Pediatric Solid Tumors

ASJC Scopus Subject Areas

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